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Doctoral position in plant metabolism and stable isotope biology (H-Shifts)

ETH Zürich -
Zürich, ZH

Jetzt bewerben

Details zur Stelle

100%
vor 8 Tagen

Qualifikationen

Biochemie
R
Physiologiekenntnisse
Laborerfahrung
Englisch
Master
Bachelor
Python

Vollständige Stellenbeschreibung

Doctoral position in plant metabolism and stable isotope biology (H-Shifts)

100%, Zurich, fixed-term

The position is part of the Swiss National Science Foundation (SNSF) project H-Shifts: "The ²H finger of plant metabolites to trace carbon metabolic shifts”. The project combines isotope biogeochemistry, plant physiology, and crop science to develop a novel tool for tracking metabolic fluxes in plants.

You will join a dynamic and interdisciplinary research team working at the interface of plant metabolism, stable isotope analysis, and crop improvement. The position sits within the Grassland Science group in the Institute of Agricultural Sciences at the Department of Environmental Systems Science at ETH Zurich, in close collaboration with the Physiological Plant Ecology group at the University of Basel where much of the work will be conducted.

Project background

Understanding how plant metabolism drives growth and yield remains a major challenge. While current approaches capture metabolite concentrations, they do not resolve metabolic fluxes – the dynamic processes underlying plant performance.

This project develops a novel approach based on natural-abundance hydrogen stable isotopes in plant carbohydrates (²H). These isotopic “fingers” encode information about key metabolic processes such as photosynthesis, carbon partitioning, and energy metabolism.

The doctoral project will contribute to three main objectives:

Develop methods to separate metabolic isotope signals from environmental (hydrological) variation
Quantify and attribute isotope signals to specific metabolic processes
Apply the approach to investigate metabolic shifts associated with soybean domestication and crop breeding

Job description

The doctoral project will involve both controlled-environment experiments and field studies.

Design and conduct plant growth experiments under controlled isotopic conditions
Sampling and preparation of plant tissues (sugars, starch, cellulose)
Stable isotope measurements (e.g., IRMS and NMR-based methods)
Data analysis and modelling of isotope signals to infer metabolic processes
Contribution to field experiments on soybean diversity and crop traits
Statistical analysis (e.g., in R or Python) and interpretation of complex datasets
Presentation of results at international conferences and publication in peer-reviewed journals

Profile

A Master’s degree in plant biology, biochemistry, environmental sciences, biogeochemistry, agronomy, ecology or a related field.
Experience or awareness of isotope applications
Experience with laboratory protocols
Interest in plant metabolism and physiology
Quantitative and statistical skills (e.g., R, Python)
Motivation to work in an interdisciplinary team
Good written and spoken English
Experience and skills working with analytical chemistry are an advantage but not required

Workplace

We offer

An interesting interdisciplinary and cross-institutional position with collaborative partners from Switzerland and France
A fully funded four-year doctoral position with competitive salary (ETH Zurich standards)
Training in cutting-edge isotope techniques and plant physiology
Access to state-of-the-art laboratory and growth facilities
Opportunities for scientific training, networking, and career development
We value diversity and promote an inclusive and respectful working environment.

We value diversity and sustainability

In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open environment that allows everyone to grow and flourish. Sustainability is a core value for us – we are consistently working towards a climate-neutral future.

Curious? So are we.

We look forward to receiving your online application by 1 July 2026 with the following documents:

Letter of motivation
CV
Bachelor's and Master's certificates with complete transcripts
Contact information of 1-2 referees

Questions regarding the position should be directed to Dr. Roland Werner, [email protected] and Dr. Meisha Holloway-Phillips, [email protected] (no applications).

Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered.

The desired starting date is no later than 1 October 2026.

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