20 beste Stellen als development program in basel, bs – aktuell auf Personalsuche

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Data Scientist (Translational Data, Transfers & Statistics – Phase I)

Ridgeline Discovery
Basel, BS

Direkt bewerben

Details zur Stelle

Teilzeit | 100%

Leistungen

Zusätzliche Urlaubstage

Qualifikationen

Doktorat
R
Klinische Erfahrung
Master
Python

Vollständige Stellenbeschreibung

About us

GRANITE BIO is a private biotechnology company located in Basel (Switzerland).

GRANITE BIO is supported by top-tier investors with ~$100M raised to date. Based on fundamental research conducted over the last two decades, GRANITE BIO’s is pursuing a differentiated approach to transform inflammatory, autoimmune, and fibrotic conditions. Both our programs are first-in-class monoclonal antibodies for large market opportunities in Immunology and Inflammation. GRT-001, the lead asset, depletes inflammatory monocytes. It has just completed a Phase 1a trial in healthy volunteers and has shown favorable safety and pharmacodynamic effect. The Phase 1b trial in patients with Ulcerative Colitis has just started. GRT-002 is an IL-3 neutralizing antibody that is thought to play an important role in type II inflammation.
We are seeking a Data Scientist with strong expertise in data transfers (DTS), statistical analysis, and translational data integration to join our Translational Science team. This role supports the progression of programs in the early clinical development stage (Phase I).
In this position, you will focus on the end-to-end lifecycle of data, including ingestion, harmonization, transfer, analysis, and interpretation of clinical PD, biomarker, and clinical datasets. You will play a key role in building scalable data pipelines, ensuring high-quality data transfers, and applying advanced statistical methods to generate actionable insights for first-in-human studies.

Responsibilities

Data Science & Statistical Analysis

Apply advanced statistical methods to analyze integrated preclinical, biomarker, and clinical datasets
Develop and implement statistical models supporting translational and exploratory analyses
Contribute to and review Statistical Analysis Plans (SAPs) with a focus on early-phase and biomarker-driven studies
Support decision-making (e.g., dose escalation, cohort expansion) through data-driven insights
Perform exploratory analyses linking PD, biomarkers, and clinical outcomes

Data Transfers & Integration (DTS)

Design, implement, and oversee data transfer specifications (DTS) across internal systems and external partners
Ensure seamless ingestion and harmonization of multi-source datasets (preclinical, clinical, omics, biomarker)
Establish and maintain robust ETL pipelines and data workflows
Ensure data consistency, traceability, and auditability across systems and studies
Collaborate with CROs and vendors to ensure timely, high-quality data delivery and transfers

Data Management & Quality

Oversee data management activities for Phase I trials with emphasis on complex and exploratory datasets
Define and enforce data standards, structures, and validation rules (e.g., CDISC where applicable)
Review key documents (DMPs, CRFs, data transfer agreements/specifications, validation plans)
Ensure data readiness for analysis, database lock, and regulatory submissions

Process & Compliance

Ensure compliance with ICH-GCP and relevant data standards
Support regulatory documentation and submissions involving biomarker and translational data
Contribute to the development of scalable, fit-for-purpose data science and DTS processes

Qualifications

MSc or PhD in Data Science, Statistics, Biostatistics, Bioinformatics, or a related field
5+ years of experience in data science, statistical analysis, or clinical/translational data environments
Strong experience with data transfers (DTS), ETL processes, and data pipeline development
Proficiency in statistical programming (e.g., R, Python, SAS)
Experience with early-phase clinical development
Solid understanding of biomarkers, PK/PD relationships, and data integration across domains
Familiarity with CDISC standards (SDTM/ADaM) and/or exploratory/non-standard datasets
Experience with ICH-GCP and relevant standards
Experience with clinical early phase studies

What we currently offer

Prime Location
Our modern laboratories and offices are located in Tech Park Basel – a leading hub for early-stage start-ups.
Commuter Benefits
We support your individual commuting needs with parking options or a commuter allowance.
Flexible Working
We offer flexible working arrangements where possible.
Additional Time Off
In addition to 24 days of annual leave, our offices and labs are closed between Christmas and New Year.
Your Birthday Off
Enjoy an extra day off to celebrate your birthday.
Coffee & Connection
Free coffee and a great space to connect with colleagues.
Personal Development
We support your professional and personal growth.
Creative Environment
Work in an innovative, dynamic, and creative setting.
Diverse Team
Join an international team of passionate and talented people.
Team Events
Regular off-site summer and winter events to connect and have fun together.

Please note that these benefits are subject to change at the company’s discretion and do not constitute a contractual entitlement.

Direkt bewerben

Erweiterte Suche

development program Jobs in basel, bs

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Ich möchte aktuelle Job-E-Mails für Stellen als development program in basel, bs erhalten

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