20 beste Stellen als project and qualification in bâle bs – aktuell auf Personalsuche

Scientist , CMC Process Chemistry
Monte Rosa Therapeutics, Inc —Basel, BS
- CHF 100’000 - CHF 130’000 pro Jahr
- 100%
- Doktorat
- Master
- Produktion
Associate Director, Global Talent Management - EU
BeiGene —Basel, BS
- CHF 152’400 - CHF 190’500 pro Jahr
- 100%
- Management-Erfahrung
- Englisch
- Analysefähigkeit
IT Support Engineer - L2
Avaso Technology Solutions —Basel, BS
- Wochenendarbeit
- Kundendienst
- Windows
- Microsoft Office
IT Desktop Support Technician (m/w/d) - limited contract of 12 months
IMI plc —Füllinsdorf, BL
- 100%
- Homeoffice
- Software-Fehlerbehebung
- Englisch
- Windows
3 Tage
Director / Associate Director – Toxicology
Monte Rosa Therapeutics, Inc —Basel, BS
- CHF 150’000 - CHF 200’000 pro Jahr
- 100%
- Doktorat
- Forschungserfahrung
- Master
8 Tage
Senior Manager, Global Commercial Contracts
BeiGene —Basel, BS
- CHF 157’400 - CHF 196’800 pro Jahr
- 100%
- Microsoft Powerpoint
- Microsoft Word
- Microsoft Excel
Concepteur/Conceptrice Cabine
SOGECLAIR —Basel, BS
- 100%
- Hybrides Arbeiten
- Microsoft Powerpoint
- Microsoft Word
- AutoCAD
Direkt bewerben
Team Lead ICT Engineering & Operations
SKAN AG —Allschwil, BL
- Informatik
- Englisch
- Master
Lead, Shore Excursions Ops
Royal Caribbean Group —Basel, BS
- Schreibfähigkeiten
- Forschungserfahrung
- Master
Director, Business Development & Alliance Management
Sobi —Basel, BS
- 100%
- Homeoffice
- Microsoft Powerpoint
- Microsoft Excel
- Management-Erfahrung
Direkt bewerben
4 Tage
Biostatistics Director
Neurocrine Bioscience —Allschwil, BL
- 100%
- Doktorat
- Datenanalyse
- Forschungserfahrung
Manager Integration Services (f/m/d)
Valora Group —Muttenz, BL
- 100%
- Homeoffice
- Englisch
- Homeoffice-Möglichkeit
- Mitarbeiterrabatt
Technical Project Manager (m/f/d)
Syngenta Crop Protection —Muttenz, BL
- 100%
- Doktorat
- Wartung
- Englisch
- Pensionskasse
Direkt bewerben
Senior Manager, Regional Process Excellence & Innovation Freight Fowarding (f/m/d)
The Peninsular and Oriental Steam Navigation Company —Basel, BS
- 100%
- Englisch
- Master
- Bachelor
Direkt bewerben
8 Tage
Associate Director/Director Study Lead
Ridgeline Discovery —Basel, BS
- 100%
- Homeoffice
- Microsoft Powerpoint
- Microsoft Word
- Microsoft Excel
Direkt bewerben
Senior Cyber Security Analyst (f/m/d) Full-time/Part-time
Baloise Group —Basel, BS
- Teilzeit
- Englisch
- AWS
- Analysefähigkeit
Lead Auditor
Bank J. Safra Sarasin AG —Basel, BS
- 100%
- Spanisch
- Englisch
- Microsoft Office
Senior Engineer Clean Utilities (m/f/d)
Exyte GmbH —Basel, BS
- CAD
- Englisch
- Microsoft Office
Post Doctoral Scientist (IHB) - Computational Immunology
Roche —Basel, BS
- 100%
- Doktorat
- Englisch
- Forschungserfahrung
Electrical Project Engineer (m/w/d)
Syngenta Crop Protection —Muttenz, BL
- 100%
- Doktorat
- Wartung
- Englisch
- Pensionskasse
Direkt bewerben

Ich möchte aktuelle Job-E-Mails für Stellen als project and qualification in bâle bs erhalten

Wenn Sie sich bei Ihrem Konto anmelden, stimmen Sie den Nutzungsbedingungen, den Richtlinien zur Verwendung von Cookies sowie der Datenschutzerklärung von SimplyHired zu.

Weitere Job-Standorte erkunden

project and qualification jobs near bâle bs

Jobs als Associate Director in Basel, BS

Jobs als Scientist in Basel, BS

Jobs als Cleaner in Basel, BS

Jobs als Account Manager in Zürich, Zh

Jobs als Quality Manager in Basel, Bs

Jobs als Tax Manager in Zürich, Zh

Jobs als Technical Project Manager in Zürich, Zh

Jobs als Internship Project Management in Zürich, Zh

Jobs als Technical Project Manager in Basel, Bs

Jobs als Director Marketing in Zürich, Zh

Jobs als Innovation Director in Geneva, Ge

Jobs als Medical Director in Basel, Bs

Jobs als Account Director in Zürich, Zh

Jobs als Associate in Genève, Ge

Jobs als Sales Associate in Geneva, Ge

Jobs als Postdoctoral Associate in Fribourg, Fr

Jobs als Ticino, Venditore, Sales Associate in Lugano, Ti

Jobs als Research Associate, Biologielaborant, Labortechniker, Laborspdzialist in Basel, Bs

Jobs als Business Analyst in Bern, Be

Jobs als Head Of Sustainability in Zürich, Zh

Scientist , CMC Process Chemistry

Monte Rosa Therapeutics, Inc
Basel, BS

Jetzt bewerben

Details zur Stelle

100% | Pensum: 90-100%
CHF 100’000 - CHF 130’000 pro Jahr

Qualifikationen

Doktorat
Klinische Erfahrung
Master
Produktion

Vollständige Stellenbeschreibung

Overview:

In this exciting role the successful candidate will contribute to CMC tasks from discovery/preclinical stage to clinical and potentially commercial stage. This includes managing outsourcing activities for development and manufacturing of drug substance from early phase onwards, including route scouting, process development and compounds supply from pre-IND to clinics. The role might imply involvement in drug product development activities from and early formulation to development and manufacturing. Strong experience in process chemistry of small molecule APIs, the desire to work in a fast-paced dynamic environment, excellent team working and cross-functional collaboration are critical in this role.

Responsibilities:

Delivery through external vendors of drug substance including route scouting, process research and development, scale-up, manufacturing and material supply activities from preclinical phase onwards with high level of independence.
Assessment or existing routes of synthesis, bottles necks identification and design of alternatives and synthesis solutions. During manufacturing and scale-up, trouble shooting, process and analytical development.
Contribute to the development and implementation of strategies to manufacture drug substance including process development, procurement of raw materials, phase appropriate analytical activities and control strategies.
Management of timelines, resources and budgets.
On assigned projects, act as CMC lead and point of contact in cross functional project teams by participating in project meetings and provide regular updates. As CMC lead, involvement into drug product development activities might also be required.
Establish a strong interaction with medicinal chemistry to support as needed early development efforts ensuring syntheses improvements as early as possible.
Liaise withtoxicology and clinical teams to seamlessly advance our small molecule development candidates into preclinical & clinical development.
Manage physico-chemical and solid state studies of small molecule drug substances including polymorphism, solubility, early formulation studies, etc. to assess developability and formulation strategies for clinical development and commercialization.
Identify, select and manage with high level of autonomy appropriate Contract Development & Manufacturing Organizations (CDMOs) for appropriate process development work and for the GMP supply of drug substance and drug product.
Prepare, review, edit CMC regulatory and quality documents (batch records, analytical validations, reports and protocols).
Liaise with the regulatory team for drafting and reviewing documents for INDs and other regulatory submissions.
Responsible for drug supply chain in preclinical and clinical trials.

Qualifications:

PhD or MSc in Organic Chemistry, Pharmaceutical Chemistry, Pharmaceutical sciences or related scientific discipline.
2-7 years of relevant experience in the pharmaceutical or biotech industry in areas such as: process chemistry , chemical or analytical development, scale-up, manufacturing (pilot or large scale), pre-formulation/formulation with small molecule drugs.
Sound knowledge of organic chemistry and process development of small molecule API.
Understanding of technical development from preclinical stage till clinical phases.
Experience of GMP manufacturing drug substances and/or drug products.
Experience of managing CDMOs and complex supply chains.
Other desirable experience: large molecule development and formulation; experience with different pharmaceutical dosage forms (e.g. tablets, capsules, parenteral, etc.), support of clinical development (Phase 1 through Phase 3) including IND, CTA and NDA filings; FDA and EMEA regulations are considered a plus, process validation/registration experience.
Needs to be highly effective in cross-functional and cross-site teams.

Jetzt bewerben

Erweiterte Suche

project and qualification Jobs in bâle bs

Scientist , CMC Process Chemistry

Associate Director, Global Talent Management - EU

IT Support Engineer - L2

IT Desktop Support Technician (m/w/d) - limited contract of 12 months

Director / Associate Director – Toxicology

Senior Manager, Global Commercial Contracts

Concepteur/Conceptrice Cabine

Team Lead ICT Engineering & Operations

Lead, Shore Excursions Ops

Director, Business Development & Alliance Management

Biostatistics Director

Manager Integration Services (f/m/d)

Technical Project Manager (m/f/d)

Senior Manager, Regional Process Excellence & Innovation Freight Fowarding (f/m/d)

Associate Director/Director Study Lead

Senior Cyber Security Analyst (f/m/d) Full-time/Part-time

Lead Auditor

Senior Engineer Clean Utilities (m/f/d)

Post Doctoral Scientist (IHB) - Computational Immunology

Electrical Project Engineer (m/w/d)

Ich möchte aktuelle Job-E-Mails für Stellen als project and qualification in bâle bs erhalten

Related Searches

Weitere Job-Standorte erkunden

Tools für Jobsuchende

Arbeitgebertools

Durchsuchen

Bleiben Sie in Kontakt