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The Institute of Molecular and Clinical Ophthalmology Basel (IOB) seeks a highly motivated Research Assistant or research Associate to join the Retinal Organoid Platform to replace a team member on maternity leave (July 2026 – January 2027). IOB is a research institute combining basic and clinical research. Its mission is to drive innovations in understanding vision and its diseases and develop new therapies for vision loss. It is a place where your expertise will be valued, your abilities challenged, and your knowledge expanded.

The Human Organoid Platform uses human retinal organoids in combination with genome engineering to create disease models and test novel gene-therapy approaches for human blinding disorders. The Human Organoid Platform is continuously developing new methodologies to improve the culture and analysis of retinal organoids, as well as implementing new read-outs for ocular disease phenotypes in retinal organoids.

Your position

In vitro culture of human pluripotent stem cells and retinal organoids
Genome engineering of pluripotent stem cells by CRISPR/Cas9, and characterization of mutant iPSC and organoids
Vector construction and molecular cloning
Analysis of retinal organoids by various histology and microscopy techniques
Applying and improving new methodologies to enhance organoid culture and analysis
Involvement in figure and paper preparation
Involvement in lab management and organization
Close collaboration with group members and IOB groups

Your profile

Master's or PHD Degree (or equivalent) in molecular biology or related field
Excellent aseptic cell culture technique
Experience with confocal microscopy and image analysis workflows
Independence in the planning, conductance, analysis and troubleshooting of molecular biology and cell culture experiments
Willingness to work with lentivirus, human tissue and standard hazardous laboratory compounds
Enthusiasm to establish and optimize new protocols and techniques
Highly organized, detail-oriented and skilled with computers
Good written and verbal communications skills
Some work during weekends and public holidays
Fluency in oral and written English

We offer you

- Scientific Excellence & Impact – Join a highly motivated research institute at the forefront of vision research, supported by state-of-the-art facilities in an international, cutting-edge research environment in Basel

An Environment Built for Performance – We create conditions that enable you to do your best work: A commitment to supporting long-term excellence and family-friendly policies
Practical Support & Accessibility – Convenient Basel location with excellent public transport, subsidized meals, childcare support, and access to university sports facilities (Unisport)
A Culture of Mutual Trust – We seek colleagues who bring motivation, innovation, and dedication; in return, we provide the resources, flexibility, and environment where exceptional work thrives

Application / Contact

Interested candidates should submit their applications online via the recruitment platform (Link). Please include a motivation letter and your Curriculum Vitae.

For further information, please visit our website www.iob.ch.

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